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. 2021 Sep 27;11(10):2525. doi: 10.3390/nano11102525

Figure 24.

Figure 24

Graphical representation of (A) the synthesis and (B) the drug delivery system of a charge-convertible CD-based nanocarrier, i.e., CDs–Pt(IV)@PEG-(PAH/DMMA). Reprinted from [302], with permission from American Chemical Society, 2016. DMMA: dimethyl maleic acid; PAH: polyacrylamide hydrochloride; PEG: polyethylene glycol; pHe: tumor extracellular pH. (a): Prolonged circulation time; (b) enhanced permeation and retention effect; (c) response to tumor extracellular pH; (d) endocytosis; (e) reduction; (f) DNA binding.