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. 2021 Oct 19;14:4283–4296. doi: 10.2147/DMSO.S320169

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© 2021 Chen et al.

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Correlations between clinical parameters and the top 20 gut microbiota in DN patients. The clinical parameters included uric acid (UA), albumin (ALB), 24-hour urine protein (24-h UP), C-reactive protein (CRP), haemoglobin A1c (HbA1c), serum cholesterol, triglycerides, estimated glomerular filtration rate (eGFR), interleukin 6 (IL-6), and haemoglobin. The gut microbiota included Bacteroides, Lactobacillus, Blautia, Klebsiella, etc. Pink indicates a positive correlation, blue indicates a negative correlation, while white indicates no correlation. *Indicates P < 0.05. **Indicates P < 0.01.