TABLE 1.
CDV isolates and CDV-positive clinical specimens
| Strain source and strain | Date and place of collection (Japan) | Vaccination historya | Age and clinical signs of patient | Type by RFLP analysis with:
|
|
|---|---|---|---|---|---|
| NdeI | FbaI | ||||
| Field isolates | |||||
| KDK-1 | 1991, Ibaraki | − | Puppy; canine distemper? (no specification) | KDK-1 | KDK-1 |
| C710D | 1994, Mie | Unknown | 2 mo; respiratory and nervous signs, bloody diarrhea | KDK-1 | KDK-1 |
| C714D | 1994, Hokkaido | − | 6 mo; lameness of right hind leg, nasal discharge | KDK-1 | KDK-1 |
| C717D | 1994, Hokkaido | + | 10 mo; diarrhea, convulsion | KDK-1 | KDK-1 |
| C720D | 1994, Hokkaido | + | 7 mo; nervous signs | KDK-1 | KDK-1 |
| Rectal swab | |||||
| 97-050b | 1997, Okayama | − | 2 mo; diarrhea, coughing, eye discharge, hard pad | NPc | NP |
| 97-063b | 1997, Tochigi | Unknown | 4 mo; canine distemper? (no specification) | NP | NP |
| 98-001d | 1998, Hokkaido | Unknown | Puppy; diarrhea | KDK-1 | KDK-1 |
| 98-002e | 1998, Chiba | − | 2 mo; diarrhea, hypersalivation, nervous signs | 98-002 | KDK-1 |
| Oral swab | |||||
| 98/001e | 1998, Chiba | − | 2 mo; diarrhea, hypersalivation, nervous signs | 98-002 | KDK-1 |
| 98/003 | 1998, Chiba | − | 2 mo; nasal discharge, vomiting, tonsillitis | KDK-1 | KDK-1 |
| 98/005 | 1998, Chiba | − | 2 mo; vomiting, respiratory signs | KDK-1 | KDK-1 |
a
Combined modified live CDV vaccine.
b
Samples 97-050 and 97-063 were positive for coronavirus.
c
NP, not performed.
d
Sample 98-001 was positive for canine parvovirus and reovirus.
e
Taken from the same patient.