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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Am J Prev Med. 2021 Jul 7;61(5):674–682. doi: 10.1016/j.amepre.2021.04.024

Table 2.

Mortality Outcomes Under Intervention Scenarios for U.S. Adults With MDEs, 2020–2100

Mental health service utilizationa Integrated cessation treatmentb (% of MPC)
Any Tx Pharm Tx 100%b increase 150% increase 200% increase MPCc
Smoking-attributable deaths avoided, 2020–2100
 Women
  No change from baseline 16,507 (4.1) 63,885 (16.0) 99,527 (25.0) 135,269 (34.0) 164,653 (41.3) 398,333
  Increase by 10% 18,142 (4.3) 70,021 (16.6) 108,841 (25.8) 147,559 (35.0) 179,212 (42.5) 422,092
  Increase by 20% 19,774 (4.5) 76,114 (17.1) 118,044 (26.6) 159,638 (36.0) 193,449 (43.6) 443,816
  100% 24,205 (4.9) 92,331 (18.8) 142,143 (28.9) 190,703 (38.8) 229,480 (46.7) 491,307
 Men
  No change from baseline 15,731 (3.6) 61,485 (14.1) 96,548 (22.1) 132,323 (30.3) 162,243 (37.1) 436,981
  Increase by 10% 17,294 (3.7) 67,466 (14.5) 105,772 (22.7) 144,705 (31.1) 177,134 (38.1) 465,389
  Increase by 20% 18,855 (3.8) 73,418 (14.9) 114,920 (23.4) 156,940 (31.9) 191,795 (39.0) 491,682
  100% 28,926 (4.7) 111,075 (18.0) 171,837 (27.8) 231,632 (37.5) 279,756 (45.2) 618,307
Life-years gained, 2020–2100
 Women
  No change from baseline 67,003 (4.0) 260,237 (15.5) 406,602 (24.2) 554,329 (33.0) 676,572 (40.2) 1,682,312
  Increase by 10% 73,644 (4.1) 285,322 (16.0) 444,873 (24.9) 605,120 (33.9) 737,048 (41.2) 1,787,406
  Increase by 20% 80,275 (4.3) 310,243 (16.5) 482,727 (25.6) 655,112 (34.8) 796,301 (42.3) 1,884,292
  100% 98,137 (4.7) 376,097 (18) 581,174 (27.7) 782,857 (37.4) 945,345 (45.1) 2,094,456
 Men
  No change from baseline 71,412 (3.5) 280,026 (13.7) 440,882 (21.5) 605,968 (29.6) 744,847 (36.4) 2,047,083
  Increase by 10% 78,509 (3.6) 307,338 (14.1) 483,187 (22.1) 663,040 (30.3) 813,788 (37.2) 2,186,660
  Increase by 20% 85,601 (3.7) 334,533 (14.4) 525,183 (22.7) 719,501 (31.1) 881,772 (38.1) 2,316,973
  100% 132,462 (4.5) 511,034 (17.2) 793,606 (26.7) 1,074,186 (36.1) 1,302,089 (43.8) 2,973,172

Notes: Estimates are for the entire population directly or indirectly affected by the intervention, including people with current MDE, former MDE, and recall error. Breakdown by MDE subgroup can be found in Appendix Tables 46.

a

Baseline levels based on proportion of smokers with current MDEs who report seeing a health professional for their depression in the National Surveys on Drug Use and Health.

b

Increased quitting under hypothetical cessation treatment interventions; Any Tx = any type of cessation treatment including behavioral, pharmacological, or a combination (13.7% increase); Pharm Tx = pharmacological cessation treatment (58.8% increase).10

c

MPC = maximum potential cessation scenario which assumes 100% of smokers using mental health services quit starting in 2020.