Table 4.
Multivariate logistic regression analyses for presence of middle ear fluid (MEF) in Coloradan children with otitis media
| Variables | n (%) | Bivariate OR (95%CI)a |
p-value | Multivariate OR (95%CI)b |
p-value |
|---|---|---|---|---|---|
| CDHR3 p.Cys529Tyr (rs6967330) | 29 (31.9) | 0.33 (0.12,0.84) | 0.02* | 0.32 (0.10,0.94) | 0.04* |
| Age (years) | 91 (100) | 1.01 (0.89,1.17) | 0.87 | 0.97 (0.81,1.16) | 0.74 |
| Male | 60 (65.9) | 1.47 (0.59,3.66) | 0.40 | 1.25 (0.41,3.74) | 0.69 |
| Not White non-Hispanic | 23(25.3) | 1.17 (0.43,3.40) | 0.77 | -- | -- |
| Attended daycare | 65 (71.4) | 2.24 (0.87,5.80) | 0.09 | 1.73 (0.52,5.86) | 0.37 |
| Allergic rhinitis (AR) | 37 (40.7) | 0.46 (0.19,1.11) | 0.09 | 0.46 (0.15,1.31) | 0.15 |
| RAOM | 66 (72.5) | 0.12 (0.02,0.44) | 0.006** | 0.10 (0.01,0.44) | 0.007** |
a
Bivariate analyses using presence of MEF at surgery as outcome variable and each listed variable as independent determinant. Average age is 3.4 years. RAOM, recurrent acute otitis media.
b
Model for multivariate analysis: MEF at surgery ~ rs6967330 + age + sex + daycare + AR + RAOM. For ethnicity, White non-Hispanic is the reference group in logistic regression, while RAOM was compared to chronic otitis media.
*
≤0.05
**
≤0.01