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. 2021 Oct 6;210(5-6):291–304. doi: 10.1007/s00430-021-00722-5

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Longitudinal HCMV sequence diversity in recipient 1012. a Variant analysis was conducted in relation to the consensus sequence from day 21. The frequency of variants (Y-axis) was plotted against the position on the genome (X-axis). The histogram on the left shows the variants binned according to their frequency percentage (X-axis) plotted against the absolute number of variants (Y-axis). b HCMV DNA load (IU/ml, left Y-axis) and pp65 antigenaemia (positive cells/400,000 leukocytes, right Y-axis) in plasma were plotted against time after transplantation (days, X-axis). Samples from four time points (days 21, 28, 35 and 50 post-transplantation) were sequenced