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. 2021 Oct 23;7:312. doi: 10.1038/s41420-021-00698-4

Fig. 4. The effects of cell death inhibitors on hippocampal inflammation and apoptosis signaling pathways.

Fig. 4

A p-NF-κB/NF-κB protein expression; B TNF-α protein expression; C the ratio of Bax/Bcl-2 protein expression; D cleaved caspase-3/procaspase-3 protein expression ratio. Data are shown as mean ± SEM. *P < 0.05 vs. Sham, P < 0.05 vs. Cardiac I/R + Vehicle; n = 6/group. Veh: cardiac I/R rats treated with vehicle; L: cardiac I/R rats treated with low dose of cell death inhibitor; M: cardiac I/R rats treated with medium dose of cell death inhibitor; H: cardiac I/R rats treated with high dose of cell death inhibitor. I/R ischemia/reperfusion injury.