TABLE 2.

HRs (95% CI) for type 2 diabetes according to quintiles of the Global Diet Quality Score in the Nurses’ Health Study II¹

	Q1	Q2	Q3	Q4	Q5	P-trend
All women
Median score	15.8	19.5	21.9	24.4	27.8
Cases, n	1647	1309	1262	1112	975
Person-years	365,779	364,667	365,382	373,363	364,174
Age- and kcal-adjusted	1	0.76 (0.71, 0.82)	0.71 (0.66, 0.76)	0.59 (0.55, 0.64)	0.48 (0.44, 0.52)	<0.001
Multivariable2	1	0.91 (0.84, 0.97)	0.94 (0.87, 1.01)	0.87 (0.80, 0.94)	0.83 (0.76, 0.91)	<0.001
Women < age 50 y
Median score	15.3	18.9	21.3	23.8	27.3
Cases, n	634	456	459	395	322
Person-years	210,566	202,881	198,185	201,222	184,898
Age- and kcal-adjusted	1	0.72 (0.64, 0.82)	0.73 (0.65, 0.83)	0.61 (0.53, 0.69)	0.50 (0.44, 0.58)	<0.001
Multivariable2	1	0.86 (0.76, 0.98)	1.00 (0.88, 1.13)	0.90 (0.79, 1.02)	0.85 (0.73, 0.98)	0.02
Women age ≥ 50 y
Median score	16.7	20.3	22.8	25.0	28.1
Cases, n	1013	853	803	717	653
Person-years	155,214	161,786	167,196	172,140	179,276
Age- and kcal-adjusted	1	0.79 (0.72, 0.86)	0.70 (0.63, 0.76)	0.58 (0.53, 0.64)	0.47 (0.43, 0.52)	<0.001
Multivariable2	1	0.93 (0.85, 1.02)	0.91 (0.82, 1.00)	0.85 (0.77, 0.94)	0.82 (0.74, 0.91)	<0.001

¹ n = 88,520. Q, quintile.

²Adjusted for age, BMI, energy intake, smoking, family history of diabetes, oral contraceptive use, menopausal status and postmenopausal hormone use (“all women” analysis only), physical activity, alcohol intake, and multivitamin use.