Table 2.

Quality evaluation of the included studies using the QUADAS tool.

	Question about study design characteristic
Study	Representative patient spectrum	Reporting of selection criteria	Reference standard	Absence of disease progression bias	Absence of partial verification bias	Absence of differential verification bias	Absence of incorporation bias	Description of index text execution	Description of reference standard execution	Reference standard blinded	Index test blinded	Absence of clinical review bias	Reporting of uninterpretable/intermediate results	Withdrawal
Schaefer	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	No	Yes	Yes	Yes
Regier	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	No	Yes	NA	Yes
Kim	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	No	Yes	NA	Yes
Schroeder	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	No	Yes	NA	Yes
Dewes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	No	Yes	Yes	Yes
Sommer	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	No	Yes	NA	Yes
Ohno	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	No	Yes	NA	Yes
Ohno	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	No	Yes	NA	Yes