Table 1.
Demographic and clinical characteristics of patients in neurosyphilis group and syphilis group.
| Characteristics | Total (n = 81) | Neurosyphilis group (n = 33) | Syphilis group (n = 48) | P value |
| Age (mean ± SD, yr) | 37.8 ± 11.8 | 39.8 ± 11.5 | 36. 5 ± 12.0 | .206 |
| Male (n, %) | 78 (96.3) | 32 (97.0) | 46 (95.8) | 1.000 |
| Marital status (n, %) | .240 | |||
| Unmarried | 48 (59.3) | 17 (51.5) | 31 (64.6) | |
| Married | 33 (40.7) | 16 (48.5) | 17 (35.4) | |
| HIV transmission route (n, %) | .010 | |||
| Heterosexual contact | 22 (27.2) | 15 (45.5) | 7 (14.6) | |
| Homosexual contact | 41 (50.6) | 11 (33.3) | 30 (62.5) | |
| Intravenous use | 1 (1.2) | 0 (0) | 1 (2.1) | |
| Not known | 17 (21.0) | 7 (21.2) | 10 (20.8) | |
| HIV/AIDS course (n, %) | .694 | |||
| Newly diagnosed | 42 (51.9) | 17 (51.5) | 25 (52.1) | |
| Within 6 mo | 14 (17.3) | 7 (21.2) | 7 (14.6) | |
| Longer than 6 mo | 25 (30.9) | 9 (27.3) | 16 (33.3) | |
| ART status (n, %) | 39 (48.1) | 6 (18.2) | 33 (68.8) | <.001 |
| OIs (n, %) | 53 (65.4) | 19 (57.6) | 34 (70.8) | .220 |
| CD4 cell count M (IQR) | 120 (31, 285) | 90 (24, 251) | 219 (48, 366) | .048 |
| CD4 cell count (n, %) | .001 | |||
| <200 cells /μL | 54 (66.7) | 29 (87.9) | 25 (52.1) | |
| ≥200 cells /μL | 27 (33.3) | 4 (12.1) | 23 (47.9) | |
| Serum HIV viral load (n, %) | .102 | |||
| ≥1000 copies/mL | 26 (72.7) | 18 (90.0) | 8 (66.7) | |
| <1000 copies/mL | 6 (27.3) | 2 (10.0) | 4 (33.3) | |
| Previous untreated with syphilis (n, %) | 61 (75.3) | 31 (93.9) | 30 (62.5) | .001 |
| Serum TRUST titer (n, %) | .007 | |||
| <1:16 | 31 (38.7) | 7 (21.2) | 24 (51.1) | |
| ≥1:16 | 49 (61.3) | 26 (78.8) | 23 (48.9) | |
| Imaging findings (n, %) | .035 | |||
| Abnormality | 20 (32.8) | 12 (48.0) | 8 (22.2) | |
| Normal | 41 (67.2) | 13 (52.0) | 28 (77.8) | |
| With symptoms and signs | ||||
| Yes | 50 (61.7) | 28 (84.8) | 22 (45.8) | <.001 |
| No | 31 (38.3) | 5 (15.2) | 26 (54.2) | |