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. 2021 Oct 23;13:116. doi: 10.1186/s13098-021-00732-6

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Effects of exercise on the morphological structure of bone. The data in the graphs are expressed as the mean ± SD, n = 6. A Using Alizarin red staining to observe the effects of two kinds of exercise on the changes of trabecular bone in the distal femoral cancellous bone of T2DM mice (4 ×). B Representative images of micro-CT analysis of the microstructure of the trabecular bone at the mouse distal femur and related indicator changes. BMD bone mineral density; BV/TV bone volume fraction; BS/BV bone surface area to bone volume ratio; BS/TV ratio of bone surface area to tissue volume; Tb.Th trabecular thickness; Tb.N trabecular number; Tb.Sp trabecular separation. C Representative images of micro-CT analysis of the microstructure of the cortical bone at the mice distal femur and related indicator changes. *P < 0.05, **P < 0.01