TABLE 3.
Number of single convalescent-phase sera reactive with and sensitivities and specificities of the various antigen preparationsa
| Antigen (testing laboratory) | No. of HGE samples reactive/no. tested | % Sensitivity (95% CI)b | No. of HME samples reactive/no. testedc | % Specificity (95% CI) | % Specificity without HME |
|---|---|---|---|---|---|
| E. equi neutrophils 1 (JHU) | 28/28 | 100 (83–100) | 1/4 | 93 (71–100) | 100 |
| E. equi neutrophils 2 (JHU) | 23/28 | 82 (62–90) | 0/4 | 100 (82–100) | 100 |
| E. equi HL60 (JHU) | 28/28 | 100 (75–97) | 3/4 | 67 (42–86) | 82 |
| Webster strain (JHU) | 27/28 | 96 (79–99) | 1/4 | 93 (79–100) | 100 |
| Spooner strain (JHU) | 26/28 | 93 (75–97) | 1/4 | 93 (71–100) | 100 |
| NY-8 strain (JHU) | 26/28 | 93 (75–97) | 1/4 | 93 (71–100) | 100 |
| NY-3 strain (NY) | 21/22 | 95 (74–98) | 1/2 | 85 (67–100) | 91 |
| NY-6 strain (NY) | 26/28 | 93 (71–95) | 3/4 | 73 (49–90) | 91 |
| NY-8 strain (NY) | 25/28 | 89 (71–95) | 3/4 | 73 (55–94) | 91 |
| HGE-2 strain (MN) | 9/9 | 100 (60–90) | 2/3 | 79 (61–97) | 91 |
a
None of the antigens reacted with sera from the RMSF or scrub typhus patients.
b
CI, confidence interval.
c
E. chaffeensis infection.