Table 4.
P-HCP 3 T neuroimaging protocol.
| Modality | Matrix | FOV (mm) | Resolu-tion (mm) | Flip Angle | TE (msec) | TR (msec) | Slices/Orient-ation | AF/ MB | Time (min: sec) |
|---|---|---|---|---|---|---|---|---|---|
| Session A | |||||||||
| Localizer | 256 | 300 | 1.72 | 15 | 3 | 40 | 1 axl,1 sag,1 cor | - | 0:10 |
| Auto Align Head Scout | 160 | 260 | 1.63 | 8 | 1.37 | 3.15 | 128 sag | - | 0:14 |
| Localizer, aligned | 256 | 300 | 1.17 | 15 | 3 | 104 | 1 axl,7 sag,1 cor | - | 0:21 |
| Spin echo field maps (AP then PA) | 104 | 208 | 2 | 90 | 66 | 8000 | 72 axl | - | 0:090:09 |
| Resting state fMRI (AP then PA) | 104 | 208 | 2 | 52 | 37 | 800 | 72 axl | - | 6:416:41 |
| T 1 w setter | 32 | 256 | 8 | 2 | 4.6 | 9.9 | 32 sag | - | 0:01 |
| T 1 w MPRAGE, multi-echo | 300 × 320 | 240 × 256 | 0.8 | 8 | 1.81, 3.6, 5.39, 7.18 | 2500 | 208 sag | AF = 2 | 8:22 |
| T 2 w setter | 32 | 256 | 8 | 2 | 6 | 13 | 32 sag | - | 0:01 |
| T 2 w turbo spin echo SPACE with volumetric navigators | 300 × 320 | 240 × 256 | 0.8 | VAR | 564 | 3200 | 208 sag | AF = 2 | 6:35 |
| Spin echo field maps (AP then PA) | 104 | 208 | 2 | 90 | 66 | 8000 | 72 axl | - | 0:090:09 |
| Task fMRI MID PA (2 runs) | 104 | 208 | 2 | 52 | 37 | 800 | 72 axl | MB = 8 | 13:4713:47 |
| Session B | |||||||||
| Localizer | 256 | 300 | 1.72 | 15 | 3 | 40 | 1 axl,1 sag,1 cor | - | 0:09 |
| AAHead Scout | 160 | 260 | 1.63 | 8 | 1.37 | 3.15 | 128 sag | - | 0:14 |
| Localizer, aligned | 256 | 300 | 1.17 | 15 | 3 | 104 | 1 axl,7 sag,1 cor | - | 0:21 |
| Spin echo field maps (AP then PA) | 104 | 208 | 2 | 90 | 66 | 8000 | 72 axl | - | 0:090:09 |
| Resting state fMRI (AP then PA) | 104 | 208 | 2 | 52 | 37 | 800 | 72 axl | MB = 8 | 6:416:41 |
| dMRI, dir98* (AP then PA) | 140 | 210 | 1.5 | 78 | 89.20 | 3230 | 92 axl | MB = 4 | 5:385:38 |
| dMRI, dir99 (AP then PA) | 140 | 210 | 1.5 | 78 | 89.20 | 3230 | 92 axl | MB = 4 | 5:425:42 |
| Spin echo field maps (AP then PA) | 104 | 208 | 2 | 90 | 66 | 8000 | 72 axl | - | 0:090:09 |
| Task fMRI DPX PA (3 runs) | 104 | 208 | 2 | 52 | 37 | 800 | 72 axl | MB = 8 | 6:116:116:11 “ |
| Task fMRI Social Cognition PA (3 runs) | 104 | 208 | 2 | 52 | 37 | 800 | 72 axl | MB = 8 | 4:074:074:07 |
Note: FOV = field of view; TE = echo time; TR = repetition time; AF = acceleration factor; MB = multi-band acceleration factor; AP = anterior-to-posterior phase encoding direction; PA = posterior-to-anterior phase encoding direction; axl = axial; sag = sagittal, cor = coronal; VAR = variable flip angle; MID = Monetary Incentive Delay; DPX = Dot Pattern Expectancy
a subset of the initial participants in the study completed the 98 direction dMRI in session A rather than session B, as described in the dMRI section above