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. 2021 Oct 25;160:261–272. doi: 10.1016/j.ejca.2021.10.009

Table 2.

Univariable analysis of patient characteristics related to fatal outcome of COVID-19. Risk (expressed in odds ratio) of a fatal outcome of COVID-19 for the different patients’ characteristics (n = 830).

All patients (n = 830)
Odds ratio (95% CI) p-value
Sex (male) 1.93 (1.41–2.64) <0.001
Age
 <65 years
 ≥65 years < 75 years 4.83 (3.04–7.67) <0.001
 ≥75 years 7.47 (4.75–11.74) <0.001
Smoking 1.47 (1.08–1.99) 0.014
Comorbidities
 Cardiovascular disease 2.38 (1.73–3.27) <0.001
 BMIa ≥ 30 0.70 (0.47–1.05) 0.081
 COPDb 1.94 (1.23–3.07) 0.004
 Diabetes mellitus 1.55 (1.07–2.26) 0.020
 Autoimmune disease 1.21 (0.65–2.23) 0.546
 Prior/other malignancy 2.78 (1.94–3.98) <0.001
 Use of steroids at COVID-19 diagnosis 1.75 (1.24–2.48) 0.002
 As part of cancer treatmentc 0.96 (0.44–2.06) 0.910
 Use >1 weekc 1.27 (0.60–2.71) 0.536
Cancer type
 Other
 Haematological malignancy 2.01 (1.40–2.89) <0.001
 Lung cancer 1.99 (1.28–3.11) 0.002
Last cancer treatment
 Surgery 0.64 (0.36–1.11) 0.107
 Radiotherapy 0.75 (0.48–1.17) 0.203
 Thoracic radiotherapy 1.24 (0.72–2.13) 0.437
 Chemotherapy 0.98 (0.72–1.33) 0.882
 Immunotherapy 0.89 (0.59–1.34) 0.563
 Targeted therapy 0.74 (0.48–1.15) 0.180
 Hormonal therapy 1.02 (0.64–1.64) 0.923
Disease stage for solid tumours
 Metastatic 0.95 (0.69–1.31) 0.768
Intention most recent cancer treatment given
 Non-curative 1.27 (0.91–1.76) 0.154

COVID-19, coronavirus disease 2019.

a

BMI, body mass index.

b

COPD, chronic obstructive pulmonary disease.

c

Within group of patients with steroids- -