Table 4.
Frequency of treatment restrictions in total group of patients with cancer and COVID-19. Number of patients in total group of patients (n = 830) with treatment restrictions, according to baseline characteristics.
| Variable | Solid tumours (n = 611) |
Haematological malignancies (n = 219) |
||
|---|---|---|---|---|
| Total n | Number of treatment restrictions — n (%)c | Total n | Number of treatment restrictions — n (%)c | |
| Age | ||||
| <65 years | 245 | 70 (28.6) | 64 | 7 (10.9) |
| ≥65 years < 75 years | 183 | 94 (51.4) | 72 | 37 (51.4) |
| ≥75 years | 183 | 139 (76.0) | 83 | 71 (85.5) |
| Sex | ||||
| Male | 308 | 173 (56.2) | 134 | 67 (50.0) |
| Female | 303 | 130 (42.9) | 85 | 48 (56.5) |
| Smoking | ||||
| Never smoked | 305 | 126 (41.3) | 94 | 46 (48.9) |
| Current smoker | 37 | 22 (59.5) | 7 | 3 (42.9) |
| History of smoking | 269 | 155 (57.6) | 88 | 50 (56.8) |
| Comorbidities | ||||
| Cardiovascular disease | 316 | 198 (62.7) | 122 | 75 (61.5) |
| BMIa≥ 30 | 135 | 64 (47.4) | 31 | 15 (48.4) |
| COPDb | 80 | 58 (72.5) | 16 | 9 (56.3) |
| Diabetes mellitus | 117 | 76 (65.0) | 36 | 23 (63.9) |
| Autoimmune disease | 35 | 17 (48.6) | 16 | 11 (68.8) |
| Prior/other malignancies | 115 | 74 (64.3) | 44 | 28 (63.6) |
| Cancer subgroups | ||||
| Lung cancer | 117 | 81 (69.2) | – | – |
| Other solid tumours | 494 | 222 (44.9) | – | – |
| Last cancer treatment | ||||
| Surgery | 84 | 33 (39.3) | – | – |
| Radiotherapy | 117 | 57 (48.7) | 5 | 3 (60.0) |
| Thoracic radiotherapy | 64 | 34 (53.1) | 2 | 1 (50.0) |
| Chemotherapy | 242 | 133 (55.0) | 97 | 56 (57.7) |
| Immunotherapy | 81 | 43 (53.1) | 59 | 30 (50.8) |
| Targeted therapy | 74 | 27 (36.5) | 57 | 38 (66.7) |
| Hormonal therapy | 95 | 44 (46.3) | – | – |
| Disease stage solid tumours | ||||
| Metastatic | 288 | 182 (63.2) | – | – |
| Outcome of COVID-19 | ||||
| Resolved | 460 | 174 (37.8) | 140 | 45 (32.1) |
| Discharged home | 247 | 79 (32.0) | 67 | 15 (22.4) |
| To revalidation centre | 31 | 24 (77.4) | 17 | 10 (58.8) |
| Fatal | 151 | 129 (85.4) | 79 | 70 (88.6) |
| Intention most recent cancer treatment given | ||||
| Curative | 285 | 98 (34.4) | 60 | 22 (36.7) |
| Non-curative | 308 | 194 (63.0) | 147 | 90 (61.2) |
| Total number of treatment restrictions | 611 | 303 (49.6) | 219 | 115 (52.5) |
COVID-19, coronavirus disease 2019.
a
BMI, body mass index.
b
COPD, chronic obstructive pulmonary disease 2.
c
Percentage is expressed as total number of patients with treatment restrictions within group of patients with the same variable.