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. 2021 Oct 1;44(5):148–152. doi: 10.18773/austprescr.2021.039

Table 2. Antihypertensive drugs that can be safely used in pregnancy.

Antihypertensive drug* Class/action Dose Adverse effects
Labetalol Beta blocker 100 mg twice a day – 400 mg three times a day Bradycardia, bronchospasm, headache
Nifedipine controlled release Calcium channel antagonist 30 mg daily – 60 mg twice a day Headache (first-dose effect), flushing, tachycardia, peripheral oedema
Methyldopa Central action 250 mg twice a day – 750 mg three times a day Depression, dry mouth, sedation, rarely haemolysis and hepatitis
Hydralazine Vasodilator 25 mg three times a day – 50 mg three times a day Flushing, headache, lupus-like syndrome
Prazosin Alpha blocker 0.5 mg twice a day – 5 mg three times a day Orthostatic hypotension
* Although oxprenolol is safe, it is no longer available in Australia.