Table 3.
Distribution of the child and maternal characteristics
| Cohort | Na | Sex (Female), % | Child age (ASC) | Child age (ADHD) | Maternal age | Parity, % | Maternal educationb, % | Maternal BMI | Maternal Alcohol (Yes), % | Maternal Smoking (Yes), % | Maternal Mental Health Problems (Yes), % | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| M | SD | M | SD | M | SD | 0 | 1 | > 2 | Low | Medium | High | M | SD | ||||||
| ALSPAC | 6200 | 50.8 | 7.7 | 0.1 | 7.7 | 0.1 | 28.9 | 4.5 | 45.8 | 36.5 | 17.7 | 20.7 | 61.9 | 17.5 | 22.8 | 3.6 | 79.8 | 19.7 | 8.5 |
| DNBC | 61,430 | 51.0 | 7.2 | 1.6 | 7.2 | 1.6 | 30.5 | 4.2 | 45.7 | 37.5 | 16.8 | 3.6 | 29.1 | 67.3 | 23.7 | 4.4 | 70.6 | 25.7 | 7.9 |
| 12.8c | 1.6c | 12.8c | 1.6c | ||||||||||||||||
| GASPII | 489 | 51.5 | 4.1 | 0.3 | 4.1 | 0.3 | 33.7 | 4.3 | 57.5 | 37.4 | 5.1 | 10.2 | 51.7 | 38.0 | 22.2 | 3.4 | 19.0 | 41.1 | 4.7 |
| Generation R | 3904 | 49.3 | 6.0 | 0.5 | 8.2 | 0.2 | 30.9 | 4.7 | 59.6 | 30.1 | 10.3 | 6.0 | 40.6 | 53.4 | 23.4 | 4.1 | 59.4 | 23.0 | 8.1 |
| INMA | 1513 | 51.6 | 4.9 | 0.6 | 4.9 | 0.6 | 32.3 | 4.1 | 57.3 | 36.6 | 6.1 | 20.9 | 41.0 | 38.1 | 23.6 | 4.2 | 9.1 | 29.8 | 17.4 |
| RHEA | 345 | 59.7 | 6.6 | 0.3 | 6.6 | 0.3 | 30.8 | 4.7 | 44.6 | 38.8 | 16.5 | 13.6 | 50.4 | 35.9 | 24.9 | 5.1 | 30.1 | 33.0 | 1.2 |
aNumber of children with data available on early acetaminophen exposure, main covariates and at least one of the outcomes studied (autistic or ADHD symptoms)
bMaternal education was not provided in DNBC. Parental socio-occupational status based on the highest of maternal or paternal education and occupation was used instead
cParent-reported questionnaire (SDQ)/Hospital diagnoses