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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Obstet Gynecol. 2021 Nov 1;138(5):747–754. doi: 10.1097/AOG.0000000000004562

Table 3.

Adjusted risk of severe maternal morbidity among patients with epilepsy compared to patients without epilepsy in California, 2007–2012 (N=2,668,442).

Exposure group N (row %) Model 1
Crude OR
(95% CI)
Model 2*
Adjusted OR
(95% CI)
Model 3
Adjusted OR
(95% CI)

Patients without epilepsy (N=2,660,297) 37,960 (1.4) Reference Reference Reference
All patients with epilepsy (N=8,145) 350 (4.3) 3.10 (2.79–3.45) 2.91 (2.61–3.24) 2.13 (1.90–2.39)
Generalized epilepsy (N=637) 49 (7.7) 5.76 (4.30–7.71) 5.32 (3.97–7.14) 3.81 (2.79–5.21)
Focal epilepsy and other less specified epilepsies (N=6,250) 241 (3.9) 2.77 (2.44–3.15) 2.61 (2.29–2.97) 2.01 (1.75–2.30)
Unspecified epilepsy complicating pregnancy, childbirth, or the puerperium (N=284) 14 (4.9) 3.58 (2.09–6.13) 3.23 (1.88–5.54) 2.31 (1.30–4.11)
Convulsions only (N=974) 46 (4.7) 3.43 (2.55–4.61) 3.20 (2.38–4.31) 1.80 (1.30–2.49)
*

Model 2 adjusted for maternal age, race or ethnicity as a social determinant, method of payment, education level, trimester of prenatal care initiation, and parity.

Model 3 additionally adjusted for validated obstetric comorbidity score. See text for details.

Refer to text for details regarding categorization of epilepsy subtypes.