Table 3.
Adjusted risk of severe maternal morbidity among patients with epilepsy compared to patients without epilepsy in California, 2007–2012 (N=2,668,442).
| Exposure group | N (row %) | Model 1 Crude OR (95% CI) |
Model 2* Adjusted OR (95% CI) |
Model 3† Adjusted OR (95% CI) |
|---|---|---|---|---|
|
| ||||
| Patients without epilepsy (N=2,660,297) | 37,960 (1.4) | Reference | Reference | Reference |
| All patients with epilepsy‡ (N=8,145) | 350 (4.3) | 3.10 (2.79–3.45) | 2.91 (2.61–3.24) | 2.13 (1.90–2.39) |
| Generalized epilepsy (N=637) | 49 (7.7) | 5.76 (4.30–7.71) | 5.32 (3.97–7.14) | 3.81 (2.79–5.21) |
| Focal epilepsy and other less specified epilepsies (N=6,250) | 241 (3.9) | 2.77 (2.44–3.15) | 2.61 (2.29–2.97) | 2.01 (1.75–2.30) |
| Unspecified epilepsy complicating pregnancy, childbirth, or the puerperium (N=284) | 14 (4.9) | 3.58 (2.09–6.13) | 3.23 (1.88–5.54) | 2.31 (1.30–4.11) |
| Convulsions only (N=974) | 46 (4.7) | 3.43 (2.55–4.61) | 3.20 (2.38–4.31) | 1.80 (1.30–2.49) |
Model 2 adjusted for maternal age, race or ethnicity as a social determinant, method of payment, education level, trimester of prenatal care initiation, and parity.
Model 3 additionally adjusted for validated obstetric comorbidity score. See text for details.
Refer to text for details regarding categorization of epilepsy subtypes.