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. Author manuscript; available in PMC: 2022 Feb 28.
Published in final edited form as: Mucosal Immunol. 2021 Aug 31;14(6):1358–1368. doi: 10.1038/s41385-021-00438-y

Figure 6. Maternal milk partially compensates for reduced lysozyme production in infant mice.

Figure 6.

a, Experimental design for assessment of maternal milk-derived lysozyme in clearance of a lysozyme sensitive S. pneumoniae strain (pgdA). At 1–2 days after birth, half of the pups from a wild-type dam and half of the pups from a lysozyme-2 deficient dam were switched. After 7 days all pups (8–9 days-old) were infected with S. pneumoniae pgdA mutant. b, CFU of nasal lavages at 7 days after IN infection with S. pneumoniae pgdA mutant in wild-type and lysozyme-2 (Lyz2−/−)-deficient infant mice (n=7–10). Data represent log10-transformed values with the mean ± SD. Statistical significance was determined using an ordinary one-way ANOVA and Dunnett’s multiple comparisons post-hoc test and is indicated as *, p ≤ 0.05.