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. Author manuscript; available in PMC: 2022 Jun 5.
Published in final edited form as: Dev Dyn. 2021 May 3;251(6):913–921. doi: 10.1002/dvdy.351

Fig. 1. Gene nomenclature for duplicated and novel genes.

Fig. 1.

a. Two Cat loci arose by gene duplication. Comparison with the human genome reveals a single copy of CAT in the human genome. Thus, Cat1 and Cat2 are paralogs in the axolotl genome. b. Annotation of orthologs and paralogs. Geneb1 is annotated based on its homology to GENEB in another organism (indicated by the pattern of exons), while a paralogous gene is annotated as Geneb2 since it has a lower sequence similarity. Grey shaded area indicates the chromosome to highlight that Geneb1 is in a different locus c. A putative novel gene family member in axolotl that has some (BLAST e-value 1e-16) similarity to a gene in another organism. d. A putative novel gene that does not have any homologs, but has a long (1941aa) open reading frame.