Table 2.
ORs (95% CI) for different outcomes associated with AIP after AIS.
| Outcomes | AIP | ||||
|---|---|---|---|---|---|
| Quartile 1 < -0.10 | Quartile 2 −0.10 to 0.08 | Quartile 3 0.08–0.26 | Quartile 4 ≥0.26 | p trend | |
| No. of cases | 366 | 366 | 366 | 365 | |
| Primary outcome | |||||
| Death and major disability (mRS, 3–6) | |||||
| No. of cases (%) | 42 (11.5) | 67 (18.3) | 70 (19.1) | 78 (21.1) | |
| Multivariable adjusted model* | 1.00 | 1.43 (1.11–1.72) | 1.62 (1.31–2.12) | 1.84 (1.23–2.53) | 0.007 |
| Secondary outcomes | |||||
| Death | |||||
| No. of cases (%) | 7 (1.9) | 5 (1.4) | 16 (4.4) | 20 (5.5) | |
| Multivariable adjusted model* | 1.00 | 0.82 (0.61–1.12) | 2.31 (1.45–2.71) | 2.64 (1.65–3.23) | 0.003 |
| Death or disability (mRS, 2–6) | |||||
| No. of cases (%) | 108 (29.5) | 126 (34.4) | 109 (29.8) | 127 (34.5) | |
| Multivariable adjusted model* | 1.00 | 1.68 (1.23–1.97) | 1.34 (1.03–1.72) | 1.73 (1.41–2.32) | 0.015 |
| Modified Rankin Scale** | |||||
| 0 (no symptoms) | 156 (42.6) | 144 (39.3) | 123 (33.6) | 104 (28.8) | |
| 1 (no significant disability despite symptoms) | 102 (27.9) | 96 (26.2) | 134 (36.6) | 134 (37.1) | |
| 2 (slight disability) | 66 (18.1) | 59 (16.1) | 39 (10.7) | 49 (13.4) | |
| 3 (moderate disability) | 19 (5.2) | 39 (10.7) | 29 (7.9) | 34 (8.8) | |
| 4 (moderately severe disability) | 15 (4.1) | 19 (5.2) | 22 (6.0) | 20 (5.5) | |
| 5 (severe disability) | 1 (0.3) | 4 (1.1) | 3 (0.8) | 4 (1.1) | |
| 6 (dead) | 7 (1.9) | 5 (1.4) | 16 (4.4) | 20 (5.5) | |
| Multivariable adjusted model | 1.00 | 1.64 (1.24–1.82) | 1.71 (1.34–1.98) | 1.82 (1.59–2.17) | 0.008 |
*
Adjustment for age, gender, and baseline NIHSS; history of lipid-lowering therapy; reperfusion therapy; history of atrial fibrillation; and history of diabetes mellitus, glucose, TC, and LDL-C.
**
Odds of a 1-U higher modified Rankin Scale score.
AIP, atherogenic index of plasma.