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. 2021 Oct 11;8:712832. doi: 10.3389/fcvm.2021.712832

Table 4.

Multivariate Cox proportional hazards analysis of cardiovascular events in ACM population.

Variable Non-adjusted P-value Model I P-value Model II P-value
LVLD (ms) 1.02 (1.00, 1.03) 0.004 1.02 (1.01, 1.03) 0.003 1.02 (1.01, 1.04) 0.002
LVLD classification
   <89.15 Reference Reference Reference
  ≥89.15 3.67 (1.77, 7.63) 0.001 4.19 (1.96, 8.95) 0.002 4.50 (1.94, 10.42) 0.001
LV GLS (%) 1.12 (1.00, 1.26) 0.056 1.14 (1.00, 1.28) 0.044 1.02 (0.86, 1.20) 0.837
LV GLS classification
   < −12.94 Reference Reference Reference
  ≥−12.94 3.34 (1.27, 8.75) 0.014 3.45 (1.31, 9.09) 0.012 1.68 (0.54, 5.22) 0.371
LV GCS (%) 1.18 (1.03, 1.35) 0.017 1.19 (1.04, 1.37) 0.013 1.18 (0.96, 1.45) 0.119
LV GCS classification
   < −13.11 Reference Reference Reference
  ≥−13.11 3.08 (1.32, 7.21) 0.010 3.28 (1.39, 7.74) 0.007 2.30 (0.90, 5.89) 0.082

Model I adjust for: age and sex.

Model II adjust for: age, sex, syncope, sustained ventricular tachycardia history, beta-blockers, family history of ACM, number of T wave inversion, major repolarization criterion, left ventricular ejection fraction, left ventricular end-diastolic volume index.

ACM, arrhythmogenic cardiomyopathy; LV, left ventricular; LVLD, left ventricular longitudinal dyssynchrony; GLS, global longitudinal strain; GCS, global circumferential strain.