Table 4.
Multivariate Cox proportional hazards analysis of cardiovascular events in ACM population.
| Variable | Non-adjusted | P-value | Model I | P-value | Model II | P-value |
|---|---|---|---|---|---|---|
| LVLD (ms) | 1.02 (1.00, 1.03) | 0.004 | 1.02 (1.01, 1.03) | 0.003 | 1.02 (1.01, 1.04) | 0.002 |
| LVLD classification | ||||||
| <89.15 | Reference | Reference | Reference | |||
| ≥89.15 | 3.67 (1.77, 7.63) | 0.001 | 4.19 (1.96, 8.95) | 0.002 | 4.50 (1.94, 10.42) | 0.001 |
| LV GLS (%) | 1.12 (1.00, 1.26) | 0.056 | 1.14 (1.00, 1.28) | 0.044 | 1.02 (0.86, 1.20) | 0.837 |
| LV GLS classification | ||||||
| < −12.94 | Reference | Reference | Reference | |||
| ≥−12.94 | 3.34 (1.27, 8.75) | 0.014 | 3.45 (1.31, 9.09) | 0.012 | 1.68 (0.54, 5.22) | 0.371 |
| LV GCS (%) | 1.18 (1.03, 1.35) | 0.017 | 1.19 (1.04, 1.37) | 0.013 | 1.18 (0.96, 1.45) | 0.119 |
| LV GCS classification | ||||||
| < −13.11 | Reference | Reference | Reference | |||
| ≥−13.11 | 3.08 (1.32, 7.21) | 0.010 | 3.28 (1.39, 7.74) | 0.007 | 2.30 (0.90, 5.89) | 0.082 |
Model I adjust for: age and sex.
Model II adjust for: age, sex, syncope, sustained ventricular tachycardia history, beta-blockers, family history of ACM, number of T wave inversion, major repolarization criterion, left ventricular ejection fraction, left ventricular end-diastolic volume index.
ACM, arrhythmogenic cardiomyopathy; LV, left ventricular; LVLD, left ventricular longitudinal dyssynchrony; GLS, global longitudinal strain; GCS, global circumferential strain.