Table 5.
Multivariate Cox proportional hazards analysis of arrhythmic events in ACM population.
| Variable | Non-adjusted | P-value | Model I | P-value | Model II | P-value |
|---|---|---|---|---|---|---|
| LVLD (ms) | 1.02 (1.00, 1.03) | 0.014 | 1.02 (1.00, 1.03) | 0.015 | 1.03 (1.01, 1.05) | 0.002 |
| LVLD classification | ||||||
| <89.15 | Reference | Reference | Reference | |||
| ≥89.15 | 3.70 (1.57, 8.72) | 0.003 | 4.02(1.65, 9.81) | 0.002 | 4.79 (1.74, 13.20) | 0.003 |
| LV GLS (%) | 1.10 (0.96, 1.26) | 0.182 | 1.10 (0.95, 1.27) | 0.187 | 1.10 (0.91, 1.35) | 0.327 |
| LV GLS classification | ||||||
| < −12.94 | Reference | Reference | Reference | |||
| ≥−12.94 | 3.01 (1.01, 8.95) | 0.047 | 3.00 (1.01, 8.95) | 0.048 | 2.00 (0.56, 7.21) | 0.287 |
| LV GCS (%) | 1.02 (0.87, 1.19) | 0.833 | 1.02 (1.87, 1.19) | 0.842 | 1.04 (0.82, 1.34) | 0.728 |
| LV GCS classification | ||||||
| < −13.11 | Reference | Reference | Reference | |||
| ≥−13.11 | 2.54 (0.99, 6.52) | 0.052 | 2.55 (0.99, 6.58) | 0.053 | 2.49 (0.85, 7.33) | 0.097 |
Model I adjust for: age and sex.
Model II adjust for: age, sex, syncope, sustained ventricular tachycardia history, beta-blockers, family history of ACM, number of T wave inversion, major repolarization criterion, left ventricular ejection fraction, left ventricular end-diastolic volume index.
ACM, arrhythmogenic cardiomyopathy; LV, left ventricular; LVLD, left ventricular longitudinal dyssynchrony; GLS, global longitudinal strain; GCS, global circumferential strain.