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. 2021 Oct 11;9:752506. doi: 10.3389/fbioe.2021.752506

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Copyright © 2021 Wu, Zhong, Yu, Rong and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Representative images (on day 7) of ALP staining of cells cultured on the unmineralized and mineralized collagen membranes. (B) ALP activity and (C) OCN content of cells. The asterisk on top of the bar indicated a statistically significant difference between groups (p < 0.05).