TABLE 1.

MicroRNAs associated to HFs.

MiRNA	Expression location in HFs	Target genes	Function in HFs
miR-10a (Lv et al., 2019)	Unknown	Bmp7	DPCs proliferation ↓
miR-22 (Yuan et al., 2015; Yan et al., 2019; Cai et al., 2020)	DPCs	Lef-1, STK40, TP63, Dlx3, Foxn1, Hoxc13	HF stem cells proliferation and differentiation ↓, keratinocyte expansion and differentiation ↓
miR-24 (Amelio et al., 2013)	IRS	Tcf-3, β-catenin	Hair keratinocyte differentiation ↑
miR-26a (Ding et al., 2020)	DPCs	Smad1	DPCs proliferation ↓
miR-29a (Ge et al., 2019)	Hair matrix, IRS	Lrp6, Ctnnb1, Bmpr1a	HF stem cells proliferation ↓, matrix proliferation ↓
miR-31 (Mardaryev et al., 2010; Kim and Yoon, 2015; Luan et al., 2017)	Hair matrix, IRS, ORS	Krt16, Krt17, Dlx3, Fgf10, STK40, LATS2, Tgf-β2	Hair keratinocyte differentiation -, matrix cells proliferation ↑
miR-137 (Dong et al., 2012)	Unknown	Mitf	Hair pigmentation ↓
miR-140 (Chen et al., 2020)	Extracellular vesicles of DPCs	Bmp2	ORS proliferation↑, matrix cells proliferation ↑
miR-148a (Lv et al., 2019)	Unknown	Bmp7	DPCs proliferation ↓
miR-195 (Liu, 2015; Zhu N. et al., 2018)	DPCs	Lrp6	HF induction of DPC ↓
miR-203 (Warshauer et al., 2015; Ma et al., 2021)	Unknown	DDOST, NAE1	Not mentioned
miR-205 (Wang et al., 2013)	HF stem cells	Inpp4b, Frk, Phlda3, Inppl1	HF stem cells proliferation ↓,progenitor cell proliferation ↓
miR-214 (Ahmed et al., 2014; Du et al., 2018)	Hair matrix	EZH2, β-catenin	HF stem cells proliferation and differentiation ↓, matrix proliferation ↓, progenitor cell migration -
miR-218 (Zhao et al., 2019)	Unknown	SFRP2	HF growth ↑, hair cycle ↑
miR-339 (Li et al., 2018)	HF stem cells	Dlx5	HF stem cells differentiation ↓

↑: promote, ↓: inhibit, -: unknown.