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. 2021 Oct 11;9:727370. doi: 10.3389/fcell.2021.727370

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Copyright © 2021 Wang, Wang, Wang, Zhou and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative micrographs show renal CD63 staining (IHC, 400×). The expression level of CD63 was significantly up-regulated in patients with FSGS compared with TBMD, which was mainly located in the cytoplasm of podocytes within non-sclerotic tuft segments (indicated by black arrows).