Table 2.
The median (interquartile range) tidal volumes and percentage of patients ventilated in the recommended range of 6–8 ml kg−1 PBW across the three studies. IQR, interquartile range; NA, not available; PBW, predicted body weight; Vt, expired tidal volume expressed as millilitres per kilogram PBW. Day 1 and day 7 are days after randomization
| Trial | Baseline Vt [ml kg−1 PBW; median (IQR)] | Baseline percentage of patients with 6–8 ml kg−1 (%) | Day 1 Vt [ml kg−1 PBW; median (IQR)] | Day 1 percentage of patients with 6–8 ml kg−1 (%) | Day 7 Vt [ml kg−1 PBW; median (IQR)] | Day 7 percentage of patients with 6–8 ml kg−1 (%) |
|---|---|---|---|---|---|---|
| OSCAR | 7.6 (6.6–9.4) | 38.5 | 7.9 (6.6–9.4) | 26.7 | 8.4 (6.9–10.3) | 28.5 |
| HARP-2 | 7.7 (6.2–9.7) | 35.9 | 9.8 (7.9–12.3) | 25.6 | 10.3 (8.3–12.6) | 19.7 |
| BALTI-2 | 8.3 (7.1–9.8) | 37.1 | NA | NA | NA | NA |