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. 2021 Oct 11;8:748137. doi: 10.3389/fcvm.2021.748137

Table 2.

Joinpoint regression analysis for mortality from non-rheumatic aortic stenosis for those aged > 45 years in Europe from 2000 to 2017.

Country Sex Trend 1 Trend 2 Trend 3 Trend 4
Years EAPC Years EAPC Years EAPC Years EAPC
Austria Males 2002–2017 5.2 (3.4–7.0)*
Females 2002–2005 8.8 (−3.0 to 22.1) 2005–2011 −0.2 (−5.2 to 5.0) 2011–2014 14.4 (−9.1 to 44.0) 2014–2017 −4.9 (−15.2 to 6.7)
Belgium Males 2000–2016 1.6 (0.5–2.7)*
Females 2000–2016 1.6 (0.9–2.3)*
Bulgaria Males 2005–2015 7.8 (−0.6 to 16.8)
Females 2005–2015 10.8 (2.4–19.9)*
Croatia Males 2002–2017 12.8 (10.2–15.5)*
Females 2002–2017 17.6 (14.3–21.0)*
Czech Males 2000–2017 8.5 (7.2–9.8)*
Republic Females 2000–2006 18.3 (13.5–23.3)* 2006–2017 5.8 (4.0–7.5)*
Denmark Males 2000–2008 9.8 (5.8–13.9)* 2008–2015 −3.7 (−8.0 to 0.8)
Females 2000–2015 1.9 (0.5–3.3)*
Estonia Males 2000–2007 15.7 (5.5–26.9)* 2007–2016 −0.7 (−6.7 to 5.8)
Females 2000–2016 8.5 (3.7–13.4)*
Finland Males 2000–2002 6.7 (−8.5 to 24.6) 2002–2005 −6.4 (−19.8 to 9.3) 2005–2008 12.0 (−4.0 to 30.7) 2008–2017 1.3 (−0.1 to 2.8)
Females 2000–2017 2.1 (1.2–3.0)*
France Males 2000–2011 2.0 (1.3–2.7)* 2011–2014 −2.5 (−7.3 to 2.6)
Females 2000–2014 0.6 (0.0–1.2)*
Germany Males 2000–2012 6.0 (5.4–6.6)* 2012–2017 −0.1 (−2.1 to 2.0)
Females 2000–2008 8.4 (7.0–9.8)* 2008–2017 0.5 (−0.6 to 1.6)
Hungary Males 2000–2017 1.8 (0.4–3.2)*
Females 2000–2017 2.5 (1.0–4.0)*
Italy Males 2003–2011 5.9 (2.8–9.1)* 2011–2016 −1.4 (−7.3 to 4.8)
Females 2003–2016 3.4 (2.5–4.3)*
Latvia Males 2000–2015 0.6 (−3.1 to 4.4)
Females 2000–2015 6.5 (3.4–9.7)*
Lithuania Males 2000–2017 5.2 (1.2–9.4)*
Females 2000–2017 10.3 (7.3–13.5)*
Netherlands Males 2000–2007 4.9 (2.2–7.7)* 2007–2017 −2.9 (−4.4 to −1.4)*
Females 2000–2007 3.2 (1.5–5.0)* 2007–2017 −1.9 (−2.8 to −0.9)*
Poland Males 2000–2017 10.6 (9.4–11.8)*
Females 2000–2012 16.6 (14.9–18.3)* 2012–2017 5.7 (−0.1 to 11.8)
Portugal Males 2007–2017 7.8 (5.3–10.3)*
Females 2007–2017 6.2 (4.0–8.4)*
Romania Males 2000–2017 2.5 (0.7–4.3)*
Females 2000–2017 5.0 (3.4–6.6)*
Slovakia Males 2000–2014 6.1 (1.3–11.0)*
Females 2000–2014 15.9 (9.9–22.4)*
Slovenia Males 2000–2017 5.1 (3.2–7.0)*
Females 2000–2017 6.4 (5.0–7.7)*
Spain Males 2000–2017 4.7 (4.0–5.3)*
Females 2000–2002 12.7 (7.9–17.7)* 2002–2007 −0.9 (−2.3 to 0.4) 2007–2010 10.0 (5.3–14.8)* 2010–2017 1.5 (1.0–2.1)*
Sweden Males 2000–2017 0.8 (0.1–1.5)*
Females 2000–2017 0.7 (0.0–1.5)
United Males 2001–2006 −0.8 (−2.5 to 0.8) 2006–2016 3.8 (3.2–4.4)*
Kingdom Females 2001–2016 2.2 (1.6–2.7)*

Where data are available. EAPC, estimated annual percentage change.

*

Statistical significance, p < 0.05.