Skip to main content
. 2021 Oct 11;12:757041. doi: 10.3389/fimmu.2021.757041

Table 2.

Laboratory parameters in different groups.

Characteristics Non-DIC, n = 48 DIC, n = 34 p
28-day mortality, n (%) 3 (6.3) 17 (50) <0.0001****
ICU stay time, days 11.3 (3.2–19.4) 15.3 (7.2–23.3) 0.0350*
APACHE II 16.7 (11.1–22.3) 20.4 (13.4–27.5) 0.0107*
SOFA 8.0 (4.1–11.9) 11.2 (7.2–15.2) 0.0005***
MV duration 81 (0–92) 157 (75–218) 0.0009***
CRRT 3 (6.3) 8 (23.5) 0.0237*
PCT 2.0 (0.5–7.3) 5.0 (2.9–21.0) 0.34
CRP 145.2 (36.8–187.3) 264.6 (125.1–351.1) <0.0001****
DIC score 3.0 (2.0–4.0) 5.0 (5.0–7.0) <0.0001****
PLT, *109/L 170.9 (59.7–282.1) 73.7 (24.3–123.1) <0.0001****
PT, s 17.0 (10.8–23.3) 22.9 (11.9–34.0) 0.0031**
Fbg, g/L 3.8 (2.2–5.4) 2.8 (1.6–3.9) 0.0015**
D-Dimer, mg/L FEU 4.3 (2.3–8.7) 16.9 (8.3–23.2) 0.0002***
Thrombotic events 9 (18.8) 15 (44) 0.0156*
Hemorrhagic events 7 (14.6) 11 (32.4) 0.0643
Blood transfusion
RBC 23 (47.9) 24 (70.6) 0.0456*
Plasma 16 (33.3) 27 (79.4) <0.0001****
PLT 4 (8.3) 10 (29.4) 0.0174*
ELA2, pg/ml 1,247 (869–1,625) 2,039 (1,544–2,534) <0.0001****
H3, pg/ml 140 (47–233) 307 (199–415) <0.0001****
Syn, pg/ml 91 (42–141) 162 (108–215) <0.0001****

DIC, disseminated intravascular coagulation; ICU, intensive care unit; APACHE, Acute Physiology and Chronic Health Evaluation; SOFA, Sequential Organ Failure Assessment; MV, mechanical ventilation; CRRT, continuous renal replacement therapy; PCT, procalcitonin; CRP, C-reactive protein; PLT, platelet; PT, prothrombin time; Fbg, fibrinogen; RBC, red blood cell; ELA2, neutrophil elastase 2; H3, citrullinated histone H3; Syn, syndecan-1.

*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.