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. 2021 Aug 13;27(6):1030–1055. doi: 10.1093/humupd/dmab022

Table IV.

Description and summary of data from studies that investigated associations between restrictive surgery and periconception outcomes of maternal health.

Author Type of bariatric surgery Studied periconception outcome Fertility Irregular menstrual cycles Vitamin status Endocrine changes Miscarriages Congenital malformations ErasmusAGE quality score
Goldman RH (2016) AGB* Fertility, irregular menstrual cycles, miscarriages = 7
Lapolla A (2010) AGB Miscarriage 6
Mead NC (2014) SG* Vitamin status
  • ↓ (fewer folate deficiencies)

  • = (Vitamin B12)

6
Günakan E (2020) SG Vitamin status = (Vitamin D) 5
Musella M (2011) Intragastric balloon Fertility 5
Pilone V (2014) SG Hormonal levels, irregular menstrual cycles ↑ (AMH) 5
Basbug A (2019) SG Congenital malformations = 4
Milone M (2017) SG Endocrine changes, fertility = (FSH, AMH) 4
Tsur A (2014) SG, gastric banding Fertility ↑/= = (Oestradiol) 4
Karadağ C (2020) SG Congenital malformations = 3
Khazraei H (2017) SG Fertility, irregular menstrual cycles, miscarriages = 3
*

AGB, adjustable gastric banding; SG, sleeve gastrectomy.

↓ indicates a decrease in the occurrence of the periconception parameter of interest, ↑ indicates an increase in the occurrence of the periconception parameter of interest and = indicates no change.