Figure 1.

Predicted three-dimensional structure and sequence alignment of LeuO. (A) Deduced amino acid sequence of A1S_1874 where the ash box indicates the helix-turn-helix DNA-binding domain (25–79) and the purple box indicates the LysR family substrate-binding domain (112–304). (B) Predicted 3D structure of A1S_1874 obtained using protein modeling server Phyre2 and PyMoL program. (C) Multiple sequence alignment using COBALT: Multiple Alignment Tool of A. baumannii A1S_1874 with previously characterized LTTR member LeuO from E. coli strain K-12, Salmonella enterica LT2, Enterobacter asburiae, and Vibrio navarrensis. “*”, “.”, “:” indicate most conserved residues and semi-conserved sequence, respectively.