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. 2021 Oct 11;12:733902. doi: 10.3389/fphar.2021.733902

FIGURE 1.

FIGURE 1

LncRNA CUST124090 (lincRNA00892) and CD40L were upregulated in CD4+ T cells of SLE patients. (A) Hierarchically clustered heatmaps of some lncRNAs that were upregulated in CD4+ T cells in SLE patients (n = 6) as compared to healthy controls (n = 6). (B) qRT-PCR was used to verify the expression of lincRNA00892 in CD4+ T cells of SLE patients (n = 36) and healthy controls (n = 28). (C) Hierarchically clustered heatmaps of some mRNAs that were upregulated in CD4+ T cells of SLE patients (n = 6) as compared to healthy controls (n = 6). (D) qRT-PCR was performed to detect the expression of CD40L in CD4+ T cells of SLE patients (n = 36) and healthy controls (n = 28). (E) Coexpression network analysis of some lncRNAs and predicted targeted mRNAs. (F) The location of both lincRNA00892 and CD40L in chromosome X. **p < 0.01, *p < 0.05. The results are expressed as mean ± standard deviation. Student’s t-test was used for comparison of two groups.