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. 2021 Oct 11;12:733902. doi: 10.3389/fphar.2021.733902

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Copyright © 2021 Liu, Lin, Wu, Wang, Xie, Wu, Qin and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LincRNA00892 mediates CD40L expression by targeting hnRNP K in primary CD4⁺ T cells. (A) RNA pulldown assay was used to identify the proteins interacted with lincRNA00892. Silver staining of the proteins pulled down by lincRNA00892. (B) The expression of hnRNP K in the gel pulled down by control, sense, and anti-sense lincRNA00892 was confirmed by western blotting. (C) The interaction between hnRNP K and lincRNA00892 (up) and CD40L (down) was identified by RIP. IgG was used as the negative control. **p < 0.01, *p < 0.05. The results are expressed as mean ± standard deviation. Student’s t-test was used for comparison of two groups.