Fig. 1.

Broad phenotyping pipeline used for analysis of Dp1Tyb mice. Diagram shows the six cohorts of Dp1Tyb mice and wild-type (WT) controls that were used in the broad phenotyping analysis. Each cohort is indicated in a different colour, showing the tests it underwent, the numbers and sex of mice involved, and the age at which the tests were administered. ABR, acoustic brainstem response; CSD, Combined SHIRPA and Dysmorphology test; DEXA, dual energy X-ray absorption; ECG, electrocardiogram; Elevated 0, elevated 0 maze; ELISA, enzyme-linked immunosorbent assay for plasma hormones; IPGTT, intraperitoneal glucose tolerance test.