Figure 2.

Temporal Changes in Cardiac Amyloidosis

Investigating the changes in incidence of cardiac amyloidosis (CA). The incidence of CA was calculated for each 5-year period of the study, adjusted for population growth per each time period. Between the first and last 5-year period (1998-2002 vs 2013-2017) the incidence of CA increased from 0.88 to 3.56 per 100,000 person-years in the entire Danish population, from 1.21 to 5.19 in men aged ≥65 years and from 1.30 to 7.18 in men aged ≥75 years. The increasing incidence of CA was most pronounced among elderly men, indicating that wild-type transthyretin amyloidosis is driving this rise.