Figure 1.

Experimental design. The rats were randomly divided into five groups; 1A, Normal control rats that received a balanced standard diet; 1B, gymnemic control rats (CGM) that received a balanced standard diet supplemented with GM; 2, diabetic rats that received a balanced standard diet and intraperitoneally injected with 60 mg/kg STZ (STZ); 3, diabetic rats that received a balanced standard diet supplemented with GM (STZ + GM) and 4, diabetic rats that were treated with glibenclamide (STZ + GL). After the 8-week experimental period, animals were sacrificed for tissue collection and PU4ii resin injection. Wk, week; GM, gymnemic acid; CGM, gymnemic control; STZ, streptozotocin; GL, glibenclamide.