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. 2021 Oct 11;22(6):1420. doi: 10.3892/etm.2021.10855

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Copyright: © Sandech et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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High magnification scanning electron micrographs of hypothalamic vascular casts at 8 weeks. (A) Control and (B) gymnemic control rats exhibited healthy small blood vessels with branching arterioles and venules, which joined further into numerous capillaries, forming a dense capillary meshwork. (C) Rats in the STZ group presented with critical arteriole and capillary shrinkage. Rats in the (D) STZ + gymnemic acid and (E) the STZ + glibenclamide groups exhibited arteriole and capillary recovery and redevelopment. Scale bars, 50 µm. yellow arrowheads, arterioles; STZ, streptozotocin; green arrowheads, venules; red arrows, capillaries.