Table I.
Comparison of blood glucose levels in different groups.
| Week | Control (mg/dl) | CGM (mg/dl) | STZ (mg/dl) | STZ+GM (mg/dl) | STZ+GL (mg/dl) |
|---|---|---|---|---|---|
| 1 | 91.8±3.9 | 104.3±4.0 | 255.7±4.8a | 368.3±14.2a,c | 207.3±19.0a |
| 2 | 99.7±4.9 | 106.8±10.5 | 348.3±31.9a | 395.5±24.8a,b | 199.3±35.9b |
| 3 | 104.2±2.6 | 109.7±2.8 | 541.2±22.6a | 318.8±39.4a,b | 166.5±29.6b |
| 4 | 96.2±2.6 | 106.0±2.2 | 383.3±53.3a | 247.0±40.3a,b | 254.0±19.3c |
| 5 | 103.0±2.1 | 96.3±2.5 | 457.2±27.0a | 230.3±44.3a,b | 190.7±14.3b |
| 6 | 102.5±2.3 | 105.2±1.8 | 418.5±13.1a | 203.3±44.9a,b | 177.7±12.2b |
| 7 | 96.7±2.3 | 110.3±2.6 | 439.0±16.8a | 273.2±44.5a,b | 121.2±10.4b |
| 8 | 89.2±3.7 | 92.7±2.4 | 413.2±11.5a | 211.0±53.0a,b | 106.2±9.7b |
Data are presented as the mean ± SEM; n=10 rats/group.
aP<0.001 vs. control;
bP<0.001 and
cP<0.01 vs. STZ. CGM, gymnemic control; GL, glibenclamide; GM, gymnemic acid; STZ, streptozotocin. The normal glucose level range of control group is 90-110 mg/dl.