Table 5.
Outcome | Group | N | In-clinic (baseline) | At-home (1–14 days) | In-clinic versus At-home Cohen’s d | CN versus MCI (In-clinic) p, Cohen’s d | CN versus MCI (At-home) p, Cohen’s d | ||
Mean (SD) | 95%CI | Mean (SD) | 95%CI | ||||||
DET speed | CN | 36 | 2.61 (0.14) | 2.57, 2.66 | 2.62 (0.11) | 2.58, 2.65 | d = –0.04 | p = 0.75, | p = 0.19, |
MCI | 40 | 2.62 (0.12) | 2.59, 2.66 | 2.65 (0.15) | 2.61, 2.7 | d = –0.27 | d = –0.08 | d = –0.30 | |
IDN speed | CN | 37 | 2.77 (0.10) | 2.74, 2.8 | 2.75 (0.07) | 2.73, 2.78 | d = 0.24 | p = 0.71, | p = 0.028, |
MCI | 40 | 2.78 (0.07) | 2.76, 2.8 | 2.79 (0.07) | 2.77, 2.81 | d = –0.17 | d = –0.09 | d = –0.51 | |
OCL accuracy | CN | 36 | 0.96 (0.11) | 0.93, 1 | 0.97 (0.11) | 0.93, 1 | d = –0.07 | p = 0.020, | p = 0.079, |
MCI | 40 | 0.90 (0.11) | 0.87, 0.94 | 0.92 (0.10) | 0.89, 0.95 | d = –0.14 | d = 0.55 | d = 0.41 | |
ONB speed | CN | 36 | 2.95 (0.08) | 2.92, 2.98 | 2.94 (0.09) | 2.91, 2.97 | d = 0.08 | p = 0.012 | p = 0.028, |
MCI | 40 | 3.00 (0.10) | 2.97, 3.03 | 2.99 (0.09) | 2.96, 3.01 | d = 0.21 | d = –0.60 | d = –0.51 | |
ONB accuracy | CN | 36 | 1.33 (0.18) | 1.27, 1.39 | 1.35 (0.13) | 1.3, 1.39 | d = –0.09 | p = 0.34 | p = 0.34, |
MCI | 40 | 1.29 (0.18) | 1.23, 1.35 | 1.31 (0.17) | 1.26, 1.37 | d = –0.11 | d = 0.22 | d = 0.22 | |
DET/IDN speed | CN | 37 | –0.38 (1.23) | –0.78, 0.02 | –0.21 (0.89) | –0.5, 0.07 | d = –0.18 | p = 0.997, | p = 0.086, |
MCI | 40 | –0.38 (0.88) | –0.65, –0.11 | –0.58 (0.95) | –0.87, –0.29 | d = 0.28 | d = –0.001 | d = 0.40 | |
OCL/ONB speed | CN | 36 | 0.03 (0.64) | –0.18, 0.24 | 0.08 (0.66) | –0.14, 0.3 | d = –0.11 | p = 0.003, | p = 0.008, |
MCI | 40 | –0.44 (0.68) | –0.65, –0.23 | –0.30 (0.55) | –0.47, –0.13 | d = –0.22 | d = 0.71 | d = 0.62 | |
LWM accuracy | CN | 36 | 0.02 (0.82) | –0.25, 0.28 | 0.10 (0.59) | –0.09, 0.29 | d = –0.11 | p = 0.061, | p = 0.11, |
MCI | 40 | –0.33 (0.78) | –0.57, –0.09 | –0.19 (0.84) | –0.45, 0.07 | d = –0.15 | d = 0.44 | d = 0.37 |
N reflects available data at first, at-home, unsupervised assessment; Data for AD dementia patients was removed (N = 3 completed an at-home assessment 1–14 days post the in-clinic baseline); p-values from independent samples t-tests; In-clinic data is for the baseline and at-home data is for the first follow-up, 1–14 days later.