Table 1.
Comparison of gender differences in risk factor profile, clinical presentation, stroke subtype, and outcome
| Variable | Men | Women | p value |
|---|---|---|---|
| Age (mean [SD]), years | 59.8 (12.7) | 60.1 (13.3) | 0.775 |
| Hypertension, n (%) | 322 (65.4) | 165 (66) | 0.881 |
| Diabetes, n (%) | 252 (51.2) | 133 (53.2) | 0.610 |
| Hyperlipidemia, n (%) | 192 (39) | 146 (58.6) | 0.000 |
| Valvular heart disease, n (%) | 20 (4.1) | 32 (12.8) | 0.000 |
| Nonvalvular atrial fibrillation, n (%) | 23 (4.7) | 9 (3.6) | 0.496 |
| Coronary artery disease, n (%) | 136 (27.6) | 29 (11.6) | 0.000 |
| Tobacco smoking, n (%) | 146 (29.6) | 0 (0.0) | 0.000 |
| Alcohol usage, n (%) | 149 (30.2) | 0 (0.0) | 0.000 |
| Clinical presentation | |||
| Weakness, n (%) | 372 (75.6) | 197 (78.8) | 0.331 |
| Aphasia, n (%) | 121 (24.6) | 70 (28) | 0.316 |
| Numbness, n (%) | 35 (7.1) | 18 (7.2) | 0.966 |
| Blood sugar at admission, mean (±SD) | 161 (75.8) | 168 (73.5) | 0.180 |
| HbA1C, mean (±SD) | 7.02 (1.68) | 7.27 (1.88) | 0.078 |
| S. total cholesterol, mean (±SD) | 181 (52.2) | 196 (50.8) | 0.000 |
| Stroke subtype | |||
| Large artery atherosclerosis, n (%) | 105 (21.3) | 37 (14.8) | 0.032 |
| Cardioembolic, n (%) | 97 (19.7) | 68 (27.2) | 0.020 |
| Valvular heart disease, n (%) | 12 (12.4) | 32 (47) | 0.0013 |
| Nonvalvular atrial fibrillation, n (%) | 50 (51.5) | 23 (33.8) | 0.024 |
| Others | 35 (36.08) | 23 (33.8) | 0.92 |
| Lacunar, n (%) | 102 (20.7) | 47 (18.8) | 0.535 |
| Admission NIHSS, mean (SD) | 8.46 (6.62) | 9.54 (6.91) | 0.039 |
| Time from onset to thrombolysis, mean (±SD), min | 194 (76.2) | 190 (85.0) | 0.755 |
| Rate of thrombolysis, n (%) | 88 (17.8) | 42 (16.8) | 0.817 |
| 1. Intravenous | 64 (72.7) | 27 (64.3) | 0.326 |
| 2. Mechanical thrombectomy | 15 (17.0) | 9 (21.4) | 0.547 |
| 3. Bridging | 9 (10.3) | 6 (14.3) | 0.561 |
| Symptomatic ICH after thrombolysis | 13 (14.7) | 0 (0.0) | 0.005 |
| In-hospital mortality, n (%) | 16 (3.3) | 12 (4.8) | 0.296 |
| mRS at 3 months, 1–2, n (%) | 326 (68.6) | 148 (61.2) | 0.046 |
| Stroke recurrence at 3 months, n (%) | 14 (2.8) | 2 (0.8) | 0.070 |
| 3-month mortality, n (%) | 31 (6.5) | 21 (8.7) | 0.294 |