Table 2.
Demographics from baseline visit (visit 1) at the time of carotid US
| Variable | Value across cohort (n = 614) | p value for association with PHV | p value for association with HV |
|---|---|---|---|
| Age (mean) | 52.78±5.28 | <0.001 | <0.001 |
| White, n (%) | 563 (83.2) | 0.001 | 0.083 |
| Female, n (%) | 394 (58.2) | <0.001 | <0.001 |
| Diabetes, n (%) | 25 (3.7) | 0.799 | 0.944 |
| Hypertension, n (%) | 119 (17.8) | 0.003 | 0.132 |
| Heart failure, n (%) | 11 (1.7) | 0.111 | 0.186 |
| History of myocardial infarction, n (%) | 8 (1.2) | 0.945 | 0.630 |
| Current cigarette smoking, n (%) | 120 (17.9) | 0.956 | 0.779 |
| Ever cigarette smoker, n (%) | 341 (50.8) | 0.513 | 0.210 |
| Current alcohol consumption, n (%) | 411 (61.3) | 0.004 | 0.158 |
| Ever alcohol drinker, n (%) | 506 (75.5) | <0.001 | 0.004 |
| Antihypertensive use, n (%) | 99 (14.8) | 0.005 | 0.07 |
| Aspirin use, n (%) | 316 (47.2) | 0.002 | 0.05 |
| Cholesterol medication use, n (%) | 6 (0.9) | 0.362 | 0.413 |
| Mean systolic blood pressure, mm Hg | 133.6±12.0 | 0.002 | <0.001 |
| BMI | 26.4±4.1 | 0.092 | 0.681 |
| LDL cholesterol (mean), mg/dL | 134.1±35.2 | 0.06 | 0.024 |
| HDL cholesterol (mean), mg/dL | 53.1±17.5 | 0.027 | 0.007 |
| Fasting blood glucose (mean), mmol/L | 100.8±20.5 | 0.116 | 0.250 |
HV, hippocampal volume; PHV, parahippocampal volume; BMI, body mass index; US, ultrasound.