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. Author manuscript; available in PMC: 2022 Mar 21.
Published in final edited form as: Nat Microbiol. 2021 Sep 21;6(10):1233–1244. doi: 10.1038/s41564-021-00972-2

Extended Data Fig. 3. A common clonotype of anti-RBD antibodies with the same binding mechanism.

Extended Data Fig. 3.

a. RBD/AZD8895 crystal structure.

b. RBD/S2E12 cryo-EM structure.

c. RBD/COV2–2381 homology model generated with Structuropedia25. COV2–2072 encodes an N-linked glycosylation sequon in the HCDR3, indicated by the gray spheres, which was modeled using the GlyProt webserver.

d. RBD/COV2–2072 homology model generated with Structuropedia25.

e. Overlay of the RBD/AZD8895 crystal structure (a) and RBD/S2E12 cryo-EM structure (b).