SagS is a hub protein, connecting multiple overlapping signaling system, to enable the transition from a planktonic to a sessile, drug tolerant mode of growth.?, unknown, Arrows and blunt-ended lines indicate stimulatory interactions and inhibitory interactions, respectively. Dashes lines indicate modulation of c-di-GMP levels. Confirmed SagS interaction partners are shown in red. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)