Figure 2.

Structural optical coherence tomography (OCT) and choroidal vascularity index (CVI) calculation of the left eye of a patient affected by drusen secondary to age-related macular degeneration. Horizontal b-scan structural OCT passing through the fovea showing the presence of drusen (A). A region of interest of 1000 µm centered to the fovea was selected (B) and binarized (C) using Niblack's auto-local threshold in order to calculate the CVI. Dark pixels represent the luminal area, whereas white pixels the stromal area. CVI was calculated as the ratio between the luminal area and the total choroidal area.