Table 1.
AMD Patients | Healthy Subjects | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Total (n = 90) | RPD (n = 30) | GA (n = 30) | Total (n = 30) | |||||||||
Mean ± SD | P Valuea | Drusen (n = 30) Mean ± SD | Mean ± SD | P Valueb | Mean ± SD | P Valueb | P Valuec | Mean ± SD | P Valueb | P Valuec | P Valued | |
Age, y | 76.6 ± 7.1 | 0.073 | 76.2 ± 8.9 | 78.2 ± 6.5 | 0.674 | 78.1 ± 5.2 | 0.719 | 1.000 | 74.0 ± 6.9 | 0.628 | 0.098 | 0.115 |
BCVA, logMAR | 0.18 ± 0.25 | <0.001 | 0.07 ± 0.08 | 0.13 ± 0.08 | 0.562 | 0.48 ± 0.33 | <0.001 | <0.001 | 0.05 ± 0.06 | 0.938 | 0.241 | <0.001 |
Axial length, mm | 23.62 ± 0.51 | 0.692 | 23.54 ± 0.46 | 23.59 ± 0.53 | 0.987 | 23.66 ± 0.52 | 0.840 | 0.959 | 23.69 ± 0.55 | 0.690 | 0.868 | 0.993 |
CMT, µm | 233 ± 42 | 0.264 | 244 ± 27 | 234 ± 43 | 0.814 | 223 ± 57 | 0.214 | 0.707 | 230 ± 33 | 0.541 | 0.968 | 0.927 |
Subfoveal ChT, µm | 191 ± 79 | <0.001 | 171 ± 48 | 192 ± 88 | 0.637 | 148 ± 77 | 0.577 | 0.071 | 253 ± 60 | <0.001 | 0.006 | <0.001 |
Mean ChT, µm | 184 ± 78 | <0.001 | 161 ± 46 | 186 ± 88 | 0.516 | 143 ± 77 | 0.728 | 0.080 | 244 ± 55 | <0.001 | 0.007 | <0.001 |
n, number; SD, standard deviation; AMD, age-related macular degeneration; RPD, reticular pseudodrusen; GA, geographic atrophy; BCVA, best-corrected visual acuity; CMT, central macular thickness; ChT, choroidal thickness.
Statistical Analysis: Analysis of variance (ANOVA) for independent samples with Tukey post hoc analysis.
ANOVA for independent samples.
Comparison with drusen group.
Comparison with RPD group.
Comparison with GA group.