Table 2.

Choroidal Analysis of the AMD Cohorts and Controls

	AMD Patients								Healthy Subjects
	Total (n = 90)			RPD (n = 30)		GA (n = 30)			Total (n = 30)
	Mean ± SD	P Valuea	Drusen (n = 30) Mean ± SD	Mean ± SD	P Valueb	Mean ± SD	P Valueb	P Valuec	Mean ± SD	P Valueb	P Valuec	P Valued
LCA, mm2 (mean ± SD)	0.0497 ± 0.0303	0.001	0.0507 ± 0.0310	0.0503 ± 0.0323	1.000	0.0330 ± 0.0270	0.079	0.090	0.0648 ± 0.0225	0.225	0.204	<0.001
SCA, mm2 (mean ± SD)	0.0745 ± 0.0170	0.125	0.0708 ± 0.0154	0.0757 ± 0.0158	0.679	0.0714 ± 0.0193	0.999	0.758	0.0801 ± 0.0165	0.152	0.747	0.198
TCA, mm2 (mean ± SD)	0.1242 ± 0.0431	0.003	0.1216 ± 0.0449	0.1260 ± 0.0452	0.975	0.1044 ± 0.0389	0.374	0.181	0.1449 ± 0.0348	0.131	0.291	<0.001
CVI, % (mean ± SD)	37.03 ± 12.59	<0.001	39.68 ± 7.87	36.09 ± 14.15	0.613	28.35 ± 14.68	0.001	0.046	43.99 ± 6.09	0.458	0.040	<0.001

n, number; SD, standard deviation; AMD, age-related macular degeneration; RPD, reticular pseudodrusen; GA, geographic atrophy; LCA, luminal choroidal area; SCA, stromal choroidal area; TCA, total choroidal area; CVI, choroidal vascularity index

Statistical Analysis: Analysis of variance (ANOVA) for independent samples with Tukey post hoc analysis.

^aANOVA for independent samples.

^bComparison with drusen group.

^cComparison with RPD group.

^dComparison with GA group.