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. 2021 Sep 6;2021(9):CD011556. doi: 10.1002/14651858.CD011556.pub2

Summary of findings 3. Biomedical feedback in addition to standard smoking cessation treatment in primary care.

Biomedical feedback in addition to standard smoking cessation treatment in primary care
Patient or population: people who attend primary care and smoke tobacco
Setting: primary care (Europe, USA)
Intervention: biomedical feedback plus standard smoking cessation support
Comparison: standard smoking cessation support
Outcomes Anticipated absolute effects* (95% CI) Relative effect
(95% CI) № of participants
(studies) Certainty of the evidence
(GRADE) Comments
Risk with placebo Risk with biomedical feedback
Smoking abstinence at 6‐month follow‐up or more Study population RR 1.07
(0.81 to 1.41) 3491
(7 RCTs) ⊕⊕⊝⊝
LOWa
10 per 100 11 per 100
(8 to 14)
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).

CI: Confidence interval; RCT: Randomized controlled trial; RR: Risk ratio
GRADE Working Group grades of evidenceHigh certainty: We are very confident that the true effect lies close to that of the estimate of the effect
Moderate certainty: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different
Low certainty: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect
Very low certainty: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect

aDowngraded two levels due to imprecision. CI encompassed the potential for both benefit and harm.