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. 2021 Sep 6;2021(9):CD011556. doi: 10.1002/14651858.CD011556.pub2

Comparison 1. Adjunctive counseling (patient‐level).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1.1 Long‐term abstinence (subgrouped by single vs. multicomponent intervention type) 22 18150 Risk Ratio (M‐H, Random, 95% CI) 1.31 [1.10, 1.55]
1.1.1 Adjunctive counseling + standard care vs standard care 17 12852 Risk Ratio (M‐H, Random, 95% CI) 1.43 [1.15, 1.78]
1.1.2 Adjunctive counseling + multicomponent int vs multicomponent int 5 5298 Risk Ratio (M‐H, Random, 95% CI) 1.04 [0.87, 1.23]
1.2 Long‐term abstinence (subgrouped by provider) 22 18150 Risk Ratio (M‐H, Random, 95% CI) 1.31 [1.10, 1.55]
1.2.1 Nurses 11 3214 Risk Ratio (M‐H, Random, 95% CI) 1.20 [0.97, 1.50]
1.2.2 Psychologists & counselors 12 14835 Risk Ratio (M‐H, Random, 95% CI) 1.31 [1.03, 1.66]
1.2.3 Pharmacists 1 101 Risk Ratio (M‐H, Random, 95% CI) 2.38 [0.99, 5.70]
1.3 Long‐term abstinence (subgrouped by mode) 22 18150 Risk Ratio (M‐H, Random, 95% CI) 1.31 [1.10, 1.55]
1.3.1 Face to face 14 11753 Risk Ratio (M‐H, Random, 95% CI) 1.31 [1.06, 1.61]
1.3.2 Telephone 10 6397 Risk Ratio (M‐H, Random, 95% CI) 1.31 [0.98, 1.75]
1.4 Long‐term abstinence (subgrouped by intensity) 22 18150 Risk Ratio (M‐H, Random, 95% CI) 1.31 [1.10, 1.55]
1.4.1 Brief/minimal 6 2533 Risk Ratio (M‐H, Random, 95% CI) 1.42 [1.07, 1.88]
1.4.2 More substantial 18 15617 Risk Ratio (M‐H, Random, 95% CI) 1.28 [1.04, 1.57]
1.5 Advise rates 2 724 Risk Ratio (M‐H, Random, 95% CI) 1.08 [0.93, 1.26]
1.5.1 Adjunctive counseling + standard care vs standard care 1 190 Risk Ratio (M‐H, Random, 95% CI) 1.20 [0.94, 1.54]
1.5.2 Adjunctive counseling + multicomponent int vs multicomponent int 1 534 Risk Ratio (M‐H, Random, 95% CI) 1.02 [0.87, 1.19]
1.6 Assistance rates 5   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
1.6.1 Medication 3 1094 Risk Ratio (M‐H, Random, 95% CI) 1.61 [1.20, 2.15]
1.6.2 Counseling 3 1460 Risk Ratio (M‐H, Random, 95% CI) 1.64 [0.94, 2.88]
1.6.3 Quit date set 1 190 Risk Ratio (M‐H, Random, 95% CI) 1.42 [0.58, 3.44]
1.6.4 Self‐help materials 1 190 Risk Ratio (M‐H, Random, 95% CI) 1.00 [0.70, 1.42]
1.7 Arrange follow‐up support rates 3   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
1.7.1 Adjunctive counseling + standard care vs standard care 3 1718 Risk Ratio (M‐H, Random, 95% CI) 4.65 [1.67, 12.90]
1.8 Quit attempts 3   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
1.8.1 Adjunctive counseling + standard care vs standard care 3 1764 Risk Ratio (M‐H, Random, 95% CI) 1.23 [1.02, 1.49]