Cobos‐Campos 2016.

Study characteristics
Methods	Design: Randomized controlled trial Setting: 2 health centres in the Basque Health Service, Spain Recruitment: Identified through EMR and sent invitation letter
Participants	320 adults who smoked, 44% female, average age 45
Interventions	Intervention: participants received health advice from a doctor or nurse, as in the other group, plus reinforcement text messages to their mobile phones Control: participants received health advice provided by a doctor or a nurse
Outcomes	Continuous abstinence at 12m Validation: Expired CO < 7 ppm
Funding Source	This study was funded by the Departamento de Industria del Gobierno Vasco of the Basque Country under the 2012 Saiotek funding round (reference number SAIO12‐OA12BF001). This research was also supported by Departamento de Educación, Política Lingüística y Cultura del Gobierno Vasco (IT620‐13)
Author's declarations of interest	Authors declared that they had no conflict of interest
Notes	Strategy: SMS messages Level: Patient Comparison type: Single component vs. standard care
Risk of bias
Bias	Authors' judgement	Support for judgement
Sequence Generation	Low risk	Computer‐generated sequence
Allocation concealment	Low risk	QUOTE: "the Bioaraba Research Institute assigned patients to one of the two arms of the trial...after receiving the patient randomization form, and hence research nurse did not know about the treatment group until patient allocation"
Blinding of outcome assessors All outcomes	Low risk	Smoking status was validated by carbon monoxide
Incomplete outcome data All outcomes	High risk	The overall loss to follow‐up was 87.5% (n = 280/320); 80.6% (n = 129/160) in the text messaging+health advice group and 94.4% (n = 151/160) in the health advice‐only group were lost to follow‐up at 12 months