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. 2021 Sep 6;2021(9):CD011556. doi: 10.1002/14651858.CD011556.pub2

Dent 2009.

Study characteristics
Methods Design: Randomized controlled trial
Setting: A Veterans Health Administration, community‐based outpatient clinic in the Rocky Mountain region, USA
Recruitment: Patients identified through EMR‐generated list. Called by pharmacist and invited to participate
Participants 101 adults who smoked 1 or more cigarettes daily for 7 days, were at least somewhat ready to quit in the next 2 weeks (≥ 4 on a 10‐point motivational scale), were willing and capable of attending 3 scheduled sessions at the clinic, and were interested in participating in the study. av.age 56, 19 cpd, 93% M
Interventions Common components in both groups: all people who smoked were referred to a clinical pharmacist via the electronic computerized patient record system. They were offered their choice of immediate‐release bupropion tablets or nicotine patch at no cost.
Intervention: participants who smoked participated in a face‐to‐face 3‐session group program at the clinic, delivered by the pharmacist and pharmacy students. For follow‐up, all participants were instructed to call the clinic for questions or to receive additional support as needed.
Control: The pharmacist or pharmacy student used a structured script and delivered 1 timed 5‐ to‐10 minute session to the participants over the telephone that included all the components of standard care recommended by the Clinical Practice Guidelines
Outcomes Continuous abstinence at 6m
Validation: Urinary cotinine < 0.3 ug/ml
Funding Source Not reported
Author's declarations of interest Not reported.
Notes Strategy: Adjunctive counseling
Level: Patient
Comparison type: Single component vs. standard care
Risk of bias
Bias Authors' judgement Support for judgement
Sequence Generation Low risk QUOTE: "Randomization codes assigned to each participant were computer generated by the study statistician and stratified by sex in blocks of 6"
Allocation concealment Low risk QUOTE: "Randomisation codes assigned to each participant were computer generated by the study statistician and stratified by sex in blocks of 6"
Blinding of outcome assessors
All outcomes Low risk Smoking status was validated by urinary cotinine
Incomplete outcome data
All outcomes Low risk The overall loss to follow‐up was 4.0% (n = 4/101); 2.0% (n = 1/50) in the intervention group and 5.9% (3/51) in the control group were lost to follow‐up at 6 months. Therefore, dropout was low and balanced between arms